G1896A Precore Mutation and Association With HBeAg Status, Genotype and Clinical Status in Patients With Chronic Hepatitis B
نویسندگان
چکیده
منابع مشابه
G1896A Precore Mutation and Association With HBeAg Status, Genotype and Clinical Status in Patients With Chronic Hepatitis B
BACKGROUND Precore stop codon (G1896A) mutation is one of the commonest mutations found in patients with chronic hepatitis B. However, over the years, this mutation was not reported much in Malaysia. OBJECTIVES We therefore investigated the presence of G1896A mutation in Malaysian population and its association with HBeAg status, clinical stage, hepatitis B virus (HBV) genotype and e-seroconv...
متن کاملg۱۸۹۶a precore mutation and association with hbeag status, genotype and clinical status in patients with chronic hepatitis b
conclusions our data suggested an intermediate prevalence of g1896a mutation among malaysian hepatitis b carriers. the stop codon mutation has a significant association with genotype b and patients with chronic hepatitis b and liver cirrhosis. patients and methods serum samples from 93 patients confirmed as hepatitis b carriers were collected for molecular assay. the whole genome of hbv was amp...
متن کاملthe past hospitalization and its association with suicide attempts and ideation in patients with mdd and comparison with bmd (depressed type) group
چکیده ندارد.
Correlation Between Hepatitis B G1896A Precore Mutations and HBeAg in Chronic HBV Patients
BACKGROUND Hepatitis B virus (HBV) infection is an important health concern worldwide, with critical outcomes. Hepatitis B e antigen (HBeAg) negative chronic hepatitis B is frequently caused by a mutation (G1896A) in the hepatitis B virus (HBV) precore (PC) reading frame, which creates a stop codon, causing premature termination of the HBe protein. OBJECTIVES This study aimed to investigate t...
متن کاملcorrelation between hepatitis b g1896a precore mutations and hbeag in chronic hbv patients
conclusions this study indicates that the rate of g1896a mutation at the pc region among hbeag negative patients, in the golestan province of iran, was similar to the average rate encountered in other parts of iran. the pc stop codon mutation was detected in 93.18% of hbeag negative patients. further studies with larger sample sizes are required to elucidate the exact role of these mutations in...
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ژورنال
عنوان ژورنال: Hepatitis Monthly
سال: 2015
ISSN: 1735-143X,1735-3408
DOI: 10.5812/hepatmon.31490